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The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments

Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease. It is a fatal degenerative disease, best recognized for its debilitating neuromuscular effects. ALS however also induces cognitive impairments in as many as 50% of affected individuals. Moreover, many ALS patien...

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Bibliografiset tiedot
Päätekijät: Thielsen, Karina D., Moser, Jakob M., Schmitt-John, Thomas, Jensen, Morten S., Jensen, Kimmo, Holm, Mai Marie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859636/
https://ncbi.nlm.nih.gov/pubmed/24349357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082767
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