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Regulation of proteasome activity in health and disease

The ubiquitin-proteasome system (UPS) is the primary selective degradation system in the nuclei and cytoplasm of eukaryotic cells, required for the turnover of myriad soluble proteins. The hundreds of factors that comprise the UPS include an enzymatic cascade that tags proteins for degradation via t...

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Detalhes bibliográficos
Main Authors: Schmidt, Marion, Finley, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858528/
https://ncbi.nlm.nih.gov/pubmed/23994620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.08.012
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