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Modelling Proteasome and Proteasome Regulator Activities

Proteasomes are key proteases involved in a variety of processes ranging from the clearance of damaged proteins to the presentation of antigens to CD8(+) T-lymphocytes. Which cleavage sites are used within the target proteins and how fast these proteins are degraded have a profound impact on immune...

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Autors principals: Liepe, Juliane, Holzhütter, Herman-Georg, Kloetzel, Peter M., Stumpf, Michael P. H., Mishto, Michele
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101499/
https://ncbi.nlm.nih.gov/pubmed/24970232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom4020585
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