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HPMA copolymer-based combination therapy toxic to both prostate cancer stem/progenitor cells and differentiated cells induces durable anti-tumor effects

Current treatments for prostate cancer are still not satisfactory, often resulting in tumor regrowth and metastasis. One of the main reasons for the ineffective anti-prostate cancer treatments is the failure to deplete cancer stem-like cells (CSCs) - a subset of cancer cells with enhanced tumorigeni...

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Detalles Bibliográficos
Autores principales: Zhou, Yan, Yang, Jiyuan, Rhim, Johng S., Kopeček, Jindřich
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858468/
https://ncbi.nlm.nih.gov/pubmed/24041709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.09.005
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