(13)C-Pyruvate Imaging Reveals Alterations in Glycolysis that Precede c-MYC Induced Tumor Formation and Regression

Tumor cells have an altered metabolic phenotype characterized by increased glycolysis and diminished oxidative phosphorylation. Despite the suspected importance of glycolysis in tumorigenesis, the temporal relationship between oncogene signaling, in vivo tumor formation and glycolytic pathway activi...

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Bibliographische Detailangaben
Hauptverfasser: Hu, Simon, Balakrishnan, Asha, Bok, Robert A., Anderton, Brittany, Larson, Peder E.Z., Nelson, Sarah J., Kurhanewicz, John, Vigneron, Daniel B., Goga, Andrei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858338/
https://ncbi.nlm.nih.gov/pubmed/21723511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.04.012
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