(13)C-Pyruvate Imaging Reveals Alterations in Glycolysis that Precede c-MYC Induced Tumor Formation and Regression

Tumor cells have an altered metabolic phenotype characterized by increased glycolysis and diminished oxidative phosphorylation. Despite the suspected importance of glycolysis in tumorigenesis, the temporal relationship between oncogene signaling, in vivo tumor formation and glycolytic pathway activi...

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Detalhes bibliográficos
Main Authors: Hu, Simon, Balakrishnan, Asha, Bok, Robert A., Anderton, Brittany, Larson, Peder E.Z., Nelson, Sarah J., Kurhanewicz, John, Vigneron, Daniel B., Goga, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858338/
https://ncbi.nlm.nih.gov/pubmed/21723511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.04.012
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