(13)C-Pyruvate Imaging Reveals Alterations in Glycolysis that Precede c-MYC Induced Tumor Formation and Regression

Tumor cells have an altered metabolic phenotype characterized by increased glycolysis and diminished oxidative phosphorylation. Despite the suspected importance of glycolysis in tumorigenesis, the temporal relationship between oncogene signaling, in vivo tumor formation and glycolytic pathway activi...

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Main Authors: Hu, Simon, Balakrishnan, Asha, Bok, Robert A., Anderton, Brittany, Larson, Peder E.Z., Nelson, Sarah J., Kurhanewicz, John, Vigneron, Daniel B., Goga, Andrei
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858338/
https://ncbi.nlm.nih.gov/pubmed/21723511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.04.012
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