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Genome-wide regulatory analysis reveals T-bet controls Th17 lineage differentiation through direct suppression of IRF4
The complex relationship between Th1 and Th17 cells is incompletely understood. The transcription factor T-bet is best known as the master regulator of Th1 lineage commitment. However, attention is now focused on the repression of alternate T cell subsets mediated by T-bet, particularly the Th17 lin...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858236/ https://ncbi.nlm.nih.gov/pubmed/24249732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202254 |
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