Improved Insulin Sensitivity despite Increased Visceral Adiposity in Mice Deficient for the Immune Cell Transcription Factor T-bet

Low-grade inflammation in fat is associated with insulin resistance, although the mechanisms are unclear. We report that mice deficient in the immune cell transcription factor T-bet have lower energy expenditure and increased visceral fat compared with wild-type mice, yet paradoxically are more insu...

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Hlavní autoři: Stolarczyk, Emilie, Vong, Chi Teng, Perucha, Esperanza, Jackson, Ian, Cawthorne, Michael A., Wargent, Edward T., Powell, Nick, Canavan, James B., Lord, Graham M., Howard, Jane K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685808/
https://ncbi.nlm.nih.gov/pubmed/23562076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.02.019
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