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Brain Atrophy Correlates with Functional Outcome in a Murine Model of Multiple Sclerosis

White matter (WM) lesions are the classic pathological hallmarks of multiple sclerosis (MS). However, MRI-based WM lesion load shows relatively poor correlation with functional outcome, resulting in the “clinico-radiological paradox” of MS. Unlike lesion based measures, volumetric MRI assessment of...

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Detalhes bibliográficos
Main Authors: Pirko, I., Johnson, A.J., Chen, Yi, Lindquist, D. M., Lohrey, A. K., Ying, J., Dunn, R. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858208/
https://ncbi.nlm.nih.gov/pubmed/20817104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2010.08.055
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