Correlation of Brain Atrophy, Disability and Spinal Cord Atrophy in a Murine Model of Multiple Sclerosis

BACKGROUND: Disability progression in multiple sclerosis (MS) remains incompletely understood. Unlike lesional measures, CNS atrophy has a strong correlation with disability. TMEV infection in SJL mice is an established model of progressive MS. We utilized in vivo MRI to quantify brain and spinal co...

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Udgivet i:J Neuroimaging
Main Authors: Paz Soldán, M. Mateo, Raman, Mekala R., Gamez, Jeffrey D., Lohrey, Anne K., Chen, Yi, Pirko, Istvan, Johnson, Aaron J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506196/
https://ncbi.nlm.nih.gov/pubmed/25893491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jon.12250
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