iTRAQ-Based Proteomic Analysis of Polyploid Giant Cancer Cells and Budding Progeny Cells Reveals Several Distinct Pathways for Ovarian Cancer Development

Polyploid giant cancer cells (PGCCs) are a morphologically distinct subgroup of human tumor cells with increased nuclear size or multiple nuclei, but they are generally considered unimportant because they are presumed to be nondividing and thus nonviable. We have recently shown that these large canc...

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Bibliographic Details
Main Authors: Zhang, Shiwu, Mercado-Uribe, Imelda, Hanash, Samir, Liu, Jinsong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858113/
https://ncbi.nlm.nih.gov/pubmed/24348907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080120
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