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Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice
Mutations in transforming growth factor beta (TGFβ) receptor type II (TGFBR2) cause Loeys–Dietz syndrome, characterized by craniofacial and cardiovascular abnormalities. Mice with a deletion of Tgfbr2 in cranial neural crest cells (Tgfbr2(fl/fl);Wnt1-Cre mice) develop cleft palate as the result of a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857953/ https://ncbi.nlm.nih.gov/pubmed/23975680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt410 |
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