Noncanonical Transforming Growth Factor β (TGFβ) Signaling in Cranial Neural Crest Cells Causes Tongue Muscle Developmental Defects

Microglossia is a congenital birth defect in humans and adversely impacts quality of life. In vertebrates, tongue muscle derives from the cranial mesoderm, whereas tendons and connective tissues in the craniofacial region originate from cranial neural crest (CNC) cells. Loss of transforming growth f...

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Detalhes bibliográficos
Main Authors: Iwata, Jun-ichi, Suzuki, Akiko, Pelikan, Richard C., Ho, Thach-Vu, Chai, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795273/
https://ncbi.nlm.nih.gov/pubmed/23950180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493551
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