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Noncanonical Transforming Growth Factor β (TGFβ) Signaling in Cranial Neural Crest Cells Causes Tongue Muscle Developmental Defects

Microglossia is a congenital birth defect in humans and adversely impacts quality of life. In vertebrates, tongue muscle derives from the cranial mesoderm, whereas tendons and connective tissues in the craniofacial region originate from cranial neural crest (CNC) cells. Loss of transforming growth f...

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Библиографические подробности
Главные авторы: Iwata, Jun-ichi, Suzuki, Akiko, Pelikan, Richard C., Ho, Thach-Vu, Chai, Yang
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795273/
https://ncbi.nlm.nih.gov/pubmed/23950180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493551
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