Enhanced Trimethylation of Histone H3 Mediates Impaired Expression of Hepatic Glucose 6-Phosphatase Expression in Offspring From Rat Dams Exposed to Hypoxia During Pregnancy

Given that hepatic glucose 6-phosphatase (G6Pase, involved in gluconeogenesis) has been demonstrated to be altered long term in animal models of intrauterine growth restriction (IUGR), we hypothesized that hypoxia in utero may regulate G6Pase expression via epigenetic mechanisms. To address this fur...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Osumek, Jessica E., Revesz, Andrew, Morton, Jude S., Davidge, Sandra T., Hardy, Daniel B.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2014
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857770/
https://ncbi.nlm.nih.gov/pubmed/23744881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719113492212
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky