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Amino acids 78 and 79 of Mammalian Orthoreovirus protein μNS are necessary for stress granule localization, core protein λ2 interaction, and de novo virus replication

At early times in Mammalian Orthoreovirus (MRV) infection, cytoplasmic inclusions termed stress granules (SGs) are formed as a component of the innate immune response, however, at later times they are no longer present despite continued immune signaling. To investigate roles of MRV proteins in SG mo...

詳細記述

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書誌詳細
主要な著者: Carroll, Kate, Hastings, Craig, Miller, Cathy L.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857589/
https://ncbi.nlm.nih.gov/pubmed/24314644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.10.009
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