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Amino acids 78 and 79 of Mammalian Orthoreovirus protein μNS are necessary for stress granule localization, core protein λ2 interaction, and de novo virus replication

At early times in Mammalian Orthoreovirus (MRV) infection, cytoplasmic inclusions termed stress granules (SGs) are formed as a component of the innate immune response, however, at later times they are no longer present despite continued immune signaling. To investigate roles of MRV proteins in SG mo...

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Hlavní autoři: Carroll, Kate, Hastings, Craig, Miller, Cathy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857589/
https://ncbi.nlm.nih.gov/pubmed/24314644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.10.009
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