Chromosomal double-strand break repair in Ku80-deficient cells.

The x-ray sensitive hamster cell line xrs-6 is deficient in DNA double-strand break (DSB) repair and exhibits impaired V(D)J recombination. The molecular defect in this line is in the 80-kDa subunit of the Ku autoantigen, a protein that binds to DNA ends and recruits the DNA-dependent protein kinase...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Liang, F, Romanienko, P J, Weaver, D T, Jeggo, P A, Jasin, M
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC38571/
https://ncbi.nlm.nih.gov/pubmed/8799130
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