Chronic Late Gestation Hypoglycemia Up-Regulates Hepatic PEPCK Associated with Increased PGC1α mRNA and pCREB in Fetal Sheep

Hepatic glucose production is normally activated at birth, but has been observed in response to experimental hypoglycemia in fetal sheep. The cellular basis for this process remains unknown. We determined the impact of 2 weeks of fetal hypoglycemia during late gestation on enzymes responsible for he...

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Detalhes bibliográficos
Main Authors: Rozance, Paul J., Limesand, Sean W., Barry, James S., Brown, Laura D., Thorn, Stephanie R., LoTurco, Dan, Regnault, Timothy R. H., Friedman, Jacob E., Hay, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857025/
https://ncbi.nlm.nih.gov/pubmed/18056789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00639.2007
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