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Increased fetal insulin concentrations for one week fail to improve insulin secretion or β-cell mass in fetal sheep with chronically reduced glucose supply

Maternal undernutrition during pregnancy and placental insufficiency are characterized by impaired development of fetal pancreatic β-cells. Prolonged reduced glucose supply to the fetus is a feature of both. It is unknown if reduced glucose supply, independent of other complications of maternal unde...

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Bibliografiske detaljer
Main Authors: Lavezzi, Jinny R., Thorn, Stephanie R., O'Meara, Meghan C., LoTurco, Dan, Brown, Laura D., Hay, William W., Rozance, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543651/
https://ncbi.nlm.nih.gov/pubmed/23135788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00413.2012
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