A physiological increase in insulin suppresses gluconeogenic gene activation in fetal sheep with sustained hypoglycemia

Reduced maternal glucose supply to the fetus and resulting fetal hypoglycemia and hypoinsulinemia activate fetal glucose production as a means to maintain cellular glucose uptake. However, this early activation of fetal glucose production may be accompanied by hepatic insulin resistance. We tested t...

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Detalhes bibliográficos
Main Authors: Thorn, Stephanie R., Sekar, Satya M., Lavezzi, Jinny R., O'Meara, Meghan C., Brown, Laura D., Hay, William W., Rozance, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Obesity, Diabetes and Energy Homeostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469666/
https://ncbi.nlm.nih.gov/pubmed/22933022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00331.2012
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