BubR1 is frequently repressed in acute myeloid leukemia and its re-expression sensitizes cells to antimitotic therapy

Spindle poison-based therapy is of only limited benefit in acute myeloid leukemia while lymphoblastic leukemia/lymphoma responds well. In this study, we demonstrated that the spindle assembly checkpoint protein BubR1 was down-regulated in the vast majority of cases of acute myeloid leukemia whereas...

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Detaylı Bibliyografya
Asıl Yazarlar: Schnerch, Dominik, Schmidts, Andrea, Follo, Marie, Udi, Josefina, Felthaus, Julia, Pfeifer, Dietmar, Engelhardt, Monika, Wäsch, Ralph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ferrata Storti Foundation 2013
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856964/
https://ncbi.nlm.nih.gov/pubmed/23812934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.087452
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