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Circular dichroism and site-directed spin labeling reveal structural and dynamical features of high-pressure states of myoglobin

Excited states of proteins may play important roles in function, yet are difficult to study spectroscopically because of their sparse population. High hydrostatic pressure increases the equilibrium population of excited states, enabling their characterization [Akasaka K (2003) Biochemistry 42:10875–...

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Bibliographic Details
Main Authors: Lerch, Michael T., Horwitz, Joseph, McCoy, John, Hubbell, Wayne L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856799/
https://ncbi.nlm.nih.gov/pubmed/24248390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320124110
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