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Mutagenesis of Isopentenyl Phosphate Kinase to Enhance Geranyl Phosphate Kinase Activity

Isopentenyl phosphate kinase (IPK) catalyzes the ATP-dependent phosphorylation of isopentenyl phosphate (IP) to form isopentenyl diphosphate (IPP) during biosynthesis of isoprenoid metabolites in Archaea. The structure of IPK from the archeaon Thermoplasma acidophilum (THA) was recently reported and...

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Autori principali: Mabanglo, Mark F., Pan, Jian-Jung, Shakya, Binita, Poulter, C. Dale
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856688/
https://ncbi.nlm.nih.gov/pubmed/22533411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300106e
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