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Mutagenesis of Isopentenyl Phosphate Kinase to Enhance Geranyl Phosphate Kinase Activity

Isopentenyl phosphate kinase (IPK) catalyzes the ATP-dependent phosphorylation of isopentenyl phosphate (IP) to form isopentenyl diphosphate (IPP) during biosynthesis of isoprenoid metabolites in Archaea. The structure of IPK from the archeaon Thermoplasma acidophilum (THA) was recently reported and...

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Detalhes bibliográficos
Main Authors: Mabanglo, Mark F., Pan, Jian-Jung, Shakya, Binita, Poulter, C. Dale
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856688/
https://ncbi.nlm.nih.gov/pubmed/22533411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300106e
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