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Membrane Pore Formation by Human Complement: Functional Importance of the Transmembrane β-Hairpin (TMH) Segments of C8α and C9
Human C8 and C9 have a key role in forming the pore-like “membrane attack complex” (MAC) of complement on bacterial cells. A possible mechanism for membrane insertion of these proteins was suggested when studies revealed a structural similarity between the MACPF domains of the C8α and C8β subunits a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856643/ https://ncbi.nlm.nih.gov/pubmed/24239861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2013.10.007 |
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