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Stereocontrolled Cyanohydrin Ether Synthesis through Chiral Brønsted Acid-Mediated Vinyl Ether Hydrocyanation

[Image: see text] Vinyl ethers can be protonated to generate oxocarbenium ions that react with Me(3)SiCN to form cyanohydrin alkyl ethers. Reactions that form racemic products proceed efficiently upon converting the vinyl ether to an α-chloro ether prior to cyanide addition in a pathway that proceed...

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Sonraí Bibleagrafaíochta
Main Authors: Lu, Chunliang, Su, Xiaoge, Floreancig, Paul E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856640/
https://ncbi.nlm.nih.gov/pubmed/23968162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo4016002
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