Development and validation of COMPASS: clinical evidence of orphan medicinal products – an assessment tool

BACKGROUND: Rare diseases are defined as life-threatening or chronically debilitating diseases with a prevalence of 50 out of 100,000 individuals or less. Orphan medicinal products (OMPs) are intended for the treatment of rare diseases. The assessment of quality of evidence in small populations is o...

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Bibliographic Details
Main Authors: Picavet, Eline, Cassiman, David, Aertgeerts, Bert, Simoens, Steven
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856624/
https://ncbi.nlm.nih.gov/pubmed/24107467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-8-157
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