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Development and validation of COMPASS: clinical evidence of orphan medicinal products – an assessment tool

BACKGROUND: Rare diseases are defined as life-threatening or chronically debilitating diseases with a prevalence of 50 out of 100,000 individuals or less. Orphan medicinal products (OMPs) are intended for the treatment of rare diseases. The assessment of quality of evidence in small populations is o...

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Detalhes bibliográficos
Main Authors: Picavet, Eline, Cassiman, David, Aertgeerts, Bert, Simoens, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856624/
https://ncbi.nlm.nih.gov/pubmed/24107467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-8-157
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