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Off-label use of orphan medicinal products: a Belgian qualitative study

BACKGROUND: Off-label use of (orphan) medicinal products for (rare) diseases is quite common but not underpinned by clinical studies to confirm efficacy and safety. No risk-analyses by regulatory agencies are carried out. The objective of this study was to map off-label use of orphan medicinal produ...

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Pubblicato in:Orphanet J Rare Dis
Autori principali: Dooms, Marc, Cassiman, David, Simoens, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086036/
https://ncbi.nlm.nih.gov/pubmed/27793155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-016-0507-y
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