The MRN protein complex genes: MRE11 and RAD50 and susceptibility to head and neck cancers

BACKGROUND: The members of MRE11/RAD50/NBN (MRN) protein complex participates in DNA double-strand break repair and DNA-damage checkpoint activation. We have previously shown that the p.I171V NBN gene mutation may contribute to the development of laryngeal cancer. This study tested the hypothesis th...

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Hlavní autoři: Ziółkowska-Suchanek, Iwona, Mosor, Maria, Wierzbicka, Małgorzata, Rydzanicz, Małgorzata, Baranowska, Marta, Nowak, Jerzy
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Short Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856607/
https://ncbi.nlm.nih.gov/pubmed/24079363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-113
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