Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate

Here we identify the amino acid transporter AnsP1 as the unique aspartate importer in the human pathogen Mycobacterium tuberculosis. Metabolomic analysis of a mutant inactivated in AnsP1 revealed the transporter is essential for M. tuberculosis to assimilate nitrogen from aspartate. Virulence of the...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Gouzy, Alexandre, Larrouy-Maumus, Gérald, Wu, Ting-Di, Peixoto, Antonio, Levillain, Florence, Lugo-Villarino, Geanncarlo, Gerquin-Kern, Jean-Luc, de Carvalho, Luiz Pedro Sório, Poquet, Yannick, Neyrolles, Olivier
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856356/
https://ncbi.nlm.nih.gov/pubmed/24077180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1355
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki