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Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate
Here we identify the amino acid transporter AnsP1 as the unique aspartate importer in the human pathogen Mycobacterium tuberculosis. Metabolomic analysis of a mutant inactivated in AnsP1 revealed the transporter is essential for M. tuberculosis to assimilate nitrogen from aspartate. Virulence of the...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856356/ https://ncbi.nlm.nih.gov/pubmed/24077180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1355 |
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