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The Dynamics of Signaling as a Pharmacological Target
Highly networked signaling hubs are often associated with disease, but targeting them pharmacologically has largely been unsuccessful in the clinic because of their functional pleiotropy. Motivated by the hypothesis that a dynamical signaling code confers functional specificity, we investigated whet...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856316/ https://ncbi.nlm.nih.gov/pubmed/24120141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.018 |
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