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The Dynamics of Signaling as a Pharmacological Target

Highly networked signaling hubs are often associated with disease, but targeting them pharmacologically has largely been unsuccessful in the clinic because of their functional pleiotropy. Motivated by the hypothesis that a dynamical signaling code confers functional specificity, we investigated whet...

詳細記述

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書誌詳細
主要な著者: Behar, Marcelo, Barken, Derren, Werner, Shannon L., Hoffmann, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856316/
https://ncbi.nlm.nih.gov/pubmed/24120141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.018
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