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Dynamic switching of calmodulin interactions underlies Ca(2+) regulation of Ca(V)1.3 channels

Calmodulin regulation of Ca(V) channels is a prominent Ca(2+) feedback mechanism orchestrating vital adjustments of Ca(2+) entry. The long-held structural correlate of this regulation has been Ca(2+)-bound calmodulin complexed alone with an IQ domain on the channel carboxy terminus. Here, however, s...

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Detalhes bibliográficos
Main Authors: Ben Johny, Manu, Yang, Philemon S., Bazzazi, Hojjat, Yue, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856249/
https://ncbi.nlm.nih.gov/pubmed/23591884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2727
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