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Allostery in Ca(2+) channel modulation by calcium binding proteins
Distinguishing between allostery and competition among modulating ligands is challenging for large target molecules. Of practical necessity, inferences are often drawn from in vitro assays on target fragments, but such inferences may belie actual mechanisms. One key example of such ambiguity concern...
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268785/ https://ncbi.nlm.nih.gov/pubmed/24441587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1436 |
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