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Oligonucleotide-Based Therapy for FTD/ALS Caused by the C9orf72 Repeat Expansion: A Perspective

Amyotrophic lateral sclerosis (ALS) is a progressive and lethal disease of motor neuron degeneration, leading to paralysis of voluntary muscles and death by respiratory failure within five years of onset. Frontotemporal dementia (FTD) is characterised by degeneration of frontal and temporal lobes, l...

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Detalhes bibliográficos
Main Authors: Fernandes, Stephanie A., Douglas, Andrew G. L., Varela, Miguel A., Wood, Matthew J. A., Aoki, Yoshitsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855979/
https://ncbi.nlm.nih.gov/pubmed/24349764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/208245
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