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The Immune Response to Intrathecal Enzyme Replacement Therapy in Mucopolysaccharidosis I Patients
BACKGROUND: Intrathecal (IT) enzyme replacement therapy with recombinant human α-l-iduronidase (rhIDU) has been studied to treat glycosaminoglycan storage in the central nervous system of mucopolysaccharidosis (MPS) I dogs and is currently being studied in MPS I patients. METHODS: We studied the imm...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855632/ https://ncbi.nlm.nih.gov/pubmed/24002329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2013.158 |
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