Brucella Induces an Unfolded Protein Response via TcpB That Supports Intracellular Replication in Macrophages

Brucella melitensis is a facultative intracellular bacterium that causes brucellosis, the most prevalent zoonosis worldwide. The Brucella intracellular replicative niche in macrophages and dendritic cells thwarts immune surveillance and complicates both therapy and vaccine development. Currently, ho...

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Hlavní autoři: Smith, Judith A., Khan, Mike, Magnani, Diogo D., Harms, Jerome S., Durward, Marina, Radhakrishnan, Girish K., Liu, Yi-Ping, Splitter, Gary A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855547/
https://ncbi.nlm.nih.gov/pubmed/24339776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003785
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