Brucella Induces an Unfolded Protein Response via TcpB That Supports Intracellular Replication in Macrophages

Brucella melitensis is a facultative intracellular bacterium that causes brucellosis, the most prevalent zoonosis worldwide. The Brucella intracellular replicative niche in macrophages and dendritic cells thwarts immune surveillance and complicates both therapy and vaccine development. Currently, ho...

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Detalhes bibliográficos
Main Authors: Smith, Judith A., Khan, Mike, Magnani, Diogo D., Harms, Jerome S., Durward, Marina, Radhakrishnan, Girish K., Liu, Yi-Ping, Splitter, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855547/
https://ncbi.nlm.nih.gov/pubmed/24339776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003785
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