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Breaking T cell tolerance to beta cell antigens by merocytic dendritic cells
In type 1 diabetes (T1D), a break in central and peripheral tolerance results in antigen-specific T cells destroying insulin-producing, pancreatic beta cells. Herein, we discuss the critical sub-population of dendritic cells responsible for mediating both the cross-presentation of islet antigen to C...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SP Birkhäuser Verlag Basel
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855359/ https://ncbi.nlm.nih.gov/pubmed/21626409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0730-6 |
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