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Merocytic dendritic cells break T cell tolerance to beta cell antigens in NOD mouse diabetes
In type 1 diabetes (T1D), the breach of central and peripheral tolerance results in autoreactive T cells destroying insulin-producing, pancreatic beta cells. Herein, we identify a critical sub-population of dendritic cells responsible for mediating both the cross-presentation of islet antigen to CD8...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916973/ https://ncbi.nlm.nih.gov/pubmed/20644171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001398 |
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