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Optimization of Tet1 ligand density in HPMA-co-oligolysine copolymers for targeted neuronal gene delivery
Targeted gene delivery vectors can enhance cellular specificity and transfection efficiency. We demonstrated previously that conjugation of Tet1, a peptide that binds to the GT1b ganglioside, to polyethylenimine results in preferential transfection of neural progenitor cells in vivo. In this work, w...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855292/ https://ncbi.nlm.nih.gov/pubmed/24041424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.08.045 |
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