Bronchial Smooth Muscle Cells of Asthmatics Promote Angiogenesis through Elevated Secretion of CXC-Chemokines (ENA-78, GRO-α, and IL-8)

BACKGROUND: Airway wall remodelling is a key pathology of asthma. It includes thickening of the airway wall, hypertrophy and hyperplasia of bronchial smooth muscle cells (BSMC), as well as an increased vascularity of the sub-epithelial cell layer. BSMC are known to be the effector cells of bronchoco...

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Detalhes bibliográficos
Main Authors: Keglowich, Laura, Roth, Michael, Philippova, Maria, Resink, Thérèse, Tjin, Gavin, Oliver, Brian, Lardinois, Didier, Dessus-Babus, Sophie, Gosens, Reinoud, Hostettler Haack, Katrin, Tamm, Michael, Borger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855263/
https://ncbi.nlm.nih.gov/pubmed/24339939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081494
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