Proteolytic Activity Present in House-Dust-Mite Extracts Degrades ENA-78/CXCL5 and Reduces Neutrophil Migration

Background. Bronchial smooth muscle cells (BSMC) are a major source of proinflammatory and proangiogenic cytokines and chemokines, including VEGF and CXC-chemokines. CXC-chemokines act primarily on neutrophils, mediating their recruitment to and activation at the site of inflammation. In humans, hou...

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Bibliografiske detaljer
Main Authors: Keglowich, Laura, Tamm, Michael, Zhong, Jun, Miglino, Nicola, Borger, Pieter
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021841/
https://ncbi.nlm.nih.gov/pubmed/24883064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/673673
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