Hypoxia Exerts Dualistic Effects on Inflammatory and Proliferative Responses of Healthy and Asthmatic Primary Human Bronchial Smooth Muscle Cells

BACKGROUND: For oxygen supply, airway wall cells depend on diffusion though the basement membrane, as well as on delivery by micro-vessels. In the asthmatic lung, local hypoxic conditions may occur due to increased thickness and altered composition of the basement membrane, as well as due to edema o...

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Bibliographic Details
Main Authors: Keglowich, Laura, Baraket, Melissa, Tamm, Michael, Borger, Peter
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933675/
https://ncbi.nlm.nih.gov/pubmed/24587090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089875
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