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Genetic and Clinical Markers of Elevated Liver Fat Content in Overweight and Obese Hispanic Children

OBJECTIVE: Genetic variation in six genes has been associated with elevated liver fat and nonalcoholic fatty liver disease in adults. We sought to determine the influence of these genes on liver fat and whether a genetic risk score (GRS) would improve upon the ability of common clinical risk factors...

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Hlavní autoři: Walker, Ryan W., Sinatra, Frank, Hartiala, Jaana, Weigensberg, Marc, Spruijt-Metz, Donna, Alderete, Tanya L., Goran, Michael I., Allayee, Hooman
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855210/
https://ncbi.nlm.nih.gov/pubmed/23804528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20523
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