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Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents

OBJECTIVE: A genome-wide study of adults identified a variant of PNPLA3 (rs738409) associated with ∼twofold higher liver fat. The purpose of this study was to examine the influence of PNPLA3 genotype on liver fat and other related metabolic outcomes in obese Hispanic children and adolescents. RESEAR...

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Detalhes bibliográficos
Main Authors: Goran, Michael I., Walker, Ryan, Le, Kim-Anne, Mahurkar, Swapna, Vikman, Susanna, Davis, Jaimie N., Spruijt-Metz, Donna, Weigensberg, Marc J., Allayee, Hooman
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992774/
https://ncbi.nlm.nih.gov/pubmed/20852027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0554
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