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Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents

OBJECTIVE: A genome-wide study of adults identified a variant of PNPLA3 (rs738409) associated with ∼twofold higher liver fat. The purpose of this study was to examine the influence of PNPLA3 genotype on liver fat and other related metabolic outcomes in obese Hispanic children and adolescents. RESEAR...

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Hlavní autoři: Goran, Michael I., Walker, Ryan, Le, Kim-Anne, Mahurkar, Swapna, Vikman, Susanna, Davis, Jaimie N., Spruijt-Metz, Donna, Weigensberg, Marc J., Allayee, Hooman
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992774/
https://ncbi.nlm.nih.gov/pubmed/20852027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0554
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