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Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription
The transcription factor c-Myc has a critical role in cell proliferation and growth. The control of ribosome biogenesis by c-Myc through the regulation of transcription mediated by all three RNA polymerases is essential for c-Myc-driven proliferation. Specifically, in the nucleolus, c-Myc has been s...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855075/ https://ncbi.nlm.nih.gov/pubmed/22665062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.227 |
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